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doi:10.1007/s00726-009-0269-0 [Pubmed] [Springer] T J de Koning
(2023b, March 29)
Pharmacological treatments may be considered in specific circumstances under specialist supervision
The current evidence base points to several overlapping molecular pathways operating in parallel: VEGFR2/Akt/eNOS Angiogenic Signalling A primary mechanistic axis involves upregulation of vascular endothelial growth factor receptor 2 (VEGFR2), leading to activation of the Akt/eNOS (endothelial nitric oxide synthase) downstream pathway
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