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It is located on human chromosome 2p16, and the protein encoded by the VRK2 gene is expressed in the human brain, testis, thymus and fetal liver [13]

The trial used oral milligram doses, not the subcutaneous microgram schedules discussed in current research communities

Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

Zaletel K, Krhin B, Gaberscek S, Bicek A, Pajic T, Hojker S