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The relation between TMAO and chronic disease can be ambiguous, involving kidney function [79], disturbed gut-blood barrier [83], or flavin-containing monooxygenase 3 genotype [84]
My top evidence-based recommendations for metabolic support: Omega-3 fatty acids (2-3g combined EPA/DHA daily): Supports GLP-1 production, reduces inflammation, and improves insulin sensitivity [16]
The 0.5 mg dose is usually used as the second step in the gradual dose-escalation schedule to help reduce side effects
10.1042/BSR20150253 15 DruckerD
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