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157 ACADSB negatively regulates the expression of GPX4 and glutathione reductase in colon cancer cells, and overexpression of ACADSB increases the concentration of MDA, Fe 2+ and lipid peroxides, inducing cell ferroptosis, and inhibiting the migration and invasion of CRC cells
The SURPASS and SURMOUNT clinical trial programs studied tirzepatide across multiple doses and populations
[28] In addition, choline inhibited obesity-induced oxidative stress and prevented hepatic accumulation of triglycerides
27 Interestingly, a meta-analysis discussed the efficacy of different types of drugs, including anti-fibrotic, anti-metabolic, and anti-apoptotic agents, on MASH and fibrosis
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