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What that means isnt always straightforward: In the Swiss study mentioned above, nearly three-quarters of primary-care docs surveyed reported using a multi-step approach (and not always the same one) when testing for B12 deficiencya practice that Miller says improves the odds of an accurate diagnosis since serum B12 levels alone dont always accurately identify a deficiency

Be more cautious in VAP, where sensitivity is only about 40%

The GLP-1 ceiling problem Even with the most effective GLP-1 therapies currently available, a significant proportion of patients do not achieve clinically optimal weight loss outcomes

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