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This putative mechanism shares similarities with metformin, the first-line medication for type 2 diabetes, rather than with incretin-based therapies

Chris Twitty Chief Scientific Officer at Skye Bioscience Both the nimacimab and the APC were dosed at 75 mg per kg every three days, with the APC additionally delivering 1 micromole per kg of a GLP-one receptor agonist peptide on the same three-day schedule

A similar approach was employed in the context of TNBC, wherein molybdenum disulfide (MoS2) was utilized as a delivery vehicle for anti-PDL1 antibody (aPDL1) and V9302, to potentiate the anti-tumor immune response in TNBC cells and markedly impede TNBC tumor growth