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For teams publishing AOD-9604 data, reporting the lot number, reconstitution diluent, and storage interval alongside assay results improves inter-laboratory comparability

In obese mice, chronic treatment with AOD-9604 increased fat oxidation and reduced weight gain, without the adverse effect on insulin sensitivity seen with intact growth hormone

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In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression