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Polymorphism in some new bis-hydrazone compounds

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GLP-1 contributes to overall maintenance of glucose homeostasis through the reduction of glucagon secretion, while preclinical evidence suggests beneficial effects on pancreatic -cell proliferation, survival, and inhibition of apoptosis [34, 36, 37]

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More recent meta-analyses confirm that digital self-monitoring, delivered via apps, wearables, or electronic scales, produces moderate weight loss and improves adherence compared to paper-based approaches, with higher engagement linked to greater weight reduction [91, 92]

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The development of taVNS in recent years has provided a non-invasive neuromodulation method that differs from previous methods requiring implantation of electrodes in the neck or diaphragm [51, 52]

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