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Tissue & organ function Investigated in mouse models where clearing senescent cells was linked to markers of fur density, fitness and renal function animal-only data
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Como agonista de melanocortinas activa MC1R, MC3R y MC4R, pero su accin funcionalmente ms relevante ocurre sobre el MC4R hipotalmico, en ncleos vinculados a la regulacin del comportamiento sexual y la excitacin
A relative deficiency of lysosomal acid lypase activity characterizes non-alcoholic fatty liver disease
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