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Participants with hepatic impairment were allocated into three groups, with the degree of impairment categorised by the investigator according to ChildPugh criteria: mild (Grade A

GLP-1 provides systemic metabolic benefits: Reduced Visceral Fat: GLP-1 preferentially mobilizes harmful visceral adiposity (fat around organs), which drives inflammation and cardiometabolic disease

Clinicians should also consider alternative medical explanations for new-onset fatigue, including thyroid dysfunction, anemia, sleep apnea (which may improve or persist despite weight loss), chronic kidney disease, or cardiovascular conditions

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