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We utilize compounded Semaglutide with Vitamin B12 or Vitamin B6, which have clinically shown to minimize these associated symptoms, leading to better tolerance and compliance
But, to deliver that triple GLP-1/GIP/glucagon effect, retatrutide is ~60 % less potent at GLP-1 than semaglutide, requiring 512 higher milligram doses (up to 12 mg weekly injections) and driving 1218% discontinuations plus ~20% dysesthesia
Lesson learned
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