The angle depends on how much fat there is at the site, which is why technique is judged case by case rather than by a fixed rule
53 Additionally, its effects on vascular tone and platelet function may increase bleeding risk, warranting caution in patients with bleeding disorders or those on blood thinners
Potential side effects include hypoglycemia (low blood sugar), joint discomfort, water retention, and jaw/facial changes with prolonged use
Biochemistry 40:1413442, PMID: 11714266 Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, JanssenHeininger YM (2006) Dynamic redox control of NF-kappaB through glutaredoxin-regulated S -glutathionylation of inhibitory kappaB kinase beta