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169 SKN reduced colonic caspase-3 expression and enhanced epithelial survival, likely contributing to its mucosal protective effects

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Lilly's phase 3 TRANSCEND-T2D-1 trial of retatrutide showed that the drug reduced A1c levels between 1.7% and 2.0%, depending on the dose, with weight loss as a percentage of starting body weight ranging between 11.5% and 16.8% after 40 weeks of treatment

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