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An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials

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A specific list of targets could include direct interference with fungal sulfur uptake via transport inhibitors, blocking EGT biosynthesis via EgtA inhibition (along with Yap1 inhibition), impeding specific steps in ETP biosynthesis (e.g., GliK), inhibition of pantothenic acid, Met and/or Cys biosynthesis or SAH degradation and finally small-molecule interference with enzymes involved in cystathionine formation in fungi

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