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Congenital deficiency of any of the six enzymes within this cycle N -acetylglutamate synthase (NAGS), carbamoyl phosphate synthase I (CPS), ornithine transcarbamylase (OTC), argininosuccinate synthetase (ASS), argininosuccinate lyase (ASL) and arginase 1 will result in a build-up of both ammonia and the substrate of the specific enzyme 4
And then, somewhere around month eight, you started noticing that your body didn't quite look the way you'd pictured it would
The NH group of Tyr631 forms a hydrogen bond with the carbonyl oxygen of pyrimidine-2,4-diones
The duration of your treatment depends entirely on you and your progress
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