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Acknowledgements This work was supported by grants from Ministerio de Economa y Competitividad (Plan Nacional de I + D + I: SAF2012-34916, and SAF2015-65679-R to F.R-P)
Brady, Professor Phil Chowienczyk, Dr Pankaj Gupta, Ms Michaela Nuttall, Mr Sam Olden, Professor Peter Sever, Dr Wayne Sunman and Dr Helen Warren
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