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In in vitro studies GLP-1 receptor agonism is associated with regulation of several inflammatory pathways, including cytokine production, lypotoxicity and macrophages differentiation
Signs that levothyroxine dose adjustment may be needed include symptoms of hyperthyroidism (anxiety, palpitations, tremor, heat intolerance) or worsening hypothyroidism (fatigue, cold intolerance, weight gain despite GLP-1 use)
The Gila monster's long fasting periods and infrequent feeding made it an interesting research subject
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