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This procedure is rarely ever performed due to risks of long-term complications The benefits of metabolic and bariatric surgery Despite the growing prescriptions for GLP-1 medications, metabolic surgery continues to be the most effective and long-lasting treatment for obesity, as well as for the remission of cardiovascular diseases, diabetes and even certain cancers

Evidence for efficacy is mixed, with some studies showing benefit and others showing no effect

2,4 Wegovy and Mounjaro also have cardiovascular outcomes work that retatrutide hasnt completed yet

References 1 NauckMAHombergerESiegelEGAllenRCEatonRPEbertRet al