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What remains unknown Despite encouraging data, genuine unknowns exist: Effects beyond 6-9 months of continuous use have not been formally studied in animals or humans
Medical uses are short term (e.g., acute conditions)
Clin Pharmacokinet 36:111 Marbury TC, Flint A, Jacobsen JB, Derving Karsbol J, Lasseter K (2017) Pharmacokinetics and tolerability of a single dose of semaglutide, a human glucagon-like peptide-1 analog, in subjects with and without renal impairment
doi: 10.1099/mic.0.000080 4 SchulzH
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