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Diospyros kaki extracted a rich source of flavonoids and polyphenols, showed significant improvements in tear volume and tear film stability, indicated by prolonged break-up time (BUT) and reduced fluorescein staining scores, demonstrating a decrease in corneal epithelial damage compared to untreated BAC controls

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SELENOP was shown to be co-localized with Alzheimers disease brain tissue lesions A plaques and neurofibrillary tangles ( choroid plexus to the CSF in Alzheimers disease patients was reported (Rueli et al., 2015)