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Glutamate, at the interface between amino acid and carbohydrate metabolism
Additionally, it also prevented depolarization of the mitochondrial membrane and suppressed mitochondrial swelling and production of mitochondrial ROS
In other words, HNMT requires healthy methylation to function
The local E GSH is assumed to affect the glutathionylation status of proteins which is an important means of regulating protein activity (Michelet et al., 2005
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