Possibly, the consistent endothelium protection during advanced healing processes in different wounds of various tissues, including blood vessels [1,2,1017], associated with the counteraction of the L-NAME-induced disturbances as well as the counteraction of the L-arginine-induced disturbances, obtained with the same BPC 157 dose range [14,15,1826], should likely compete with the prominent endothelium effect of the heparin-impaired endothelial nitric oxide (NO) synthesis [36] as well as warfarin endothelium damage [37]
In reality, starting high increases side effects, makes it impossible to identify your true minimum effective dose, and may actually reduce effectiveness if receptor downregulation occurs
(PubMed) Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC
Infants, kids, adults, and seniors have different needs based on their health and age