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Similar to stimulation with GPBAR-A, PGE 2 -stimulated cAMP levels were lower in cells expressing hGPR17L than control-transduced cells treated with 100 nM MDL29,951

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1 The findings were significant: Those not taking GLP-1 medications showed significantly more MS disease progression Higher risk of brainstem dysfunction (4.36% risk difference) Higher risk of cerebellar dysfunction (4.54% risk difference) Higher risk of bowel and bladder dysfunction (4.98% risk difference) Research from Johns Hopkins University found that GLP-1 receptor agonists delayed disease onset and reduced severity in animal models of MS

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