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Mutation: CAT gene
with the average age of onset being between 1 to 2 years after birth
Astrocytes are specialized cells in the brain and spinal cord
no recessive alleles for chocolate/liver brown are present
Bewegung Induzierte Metabolische Myopathie (EIMM/CNM) - Deutscher Jagdterrier Hundebesitzer Mutation: CAT geneExercise induced metabolic myopathy (EIMM) is an inherited muscle disease. Clinical signs include exercise induced muscle pain, suspected rhabdomyolysis, exercise intolerance and weakness. So far, the disease was only described in German Hunting Terriers. Affected dogs cannot be used for hunting as they collapse and develop tetraparesis or tetraplegia shortly after exercise. During these episodes, affected dogs present a brownish discoloration of the
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